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1

Total synthesis of ionophore antibiotic X-14547 A (indanomycin)

Burke, Steven D., Piscopio, Anthony D., Kort, Michael E., Matulenko, Mark A., Parker, Marshall H., Armistead, David M., Shankaran, K.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 2.90 MB

english, 1994

2

4-Amino-5-aryl-6-arylethynylpyrimidines: Structure–activity relationships of non-nucleoside adenosine kinase inhibitors

Mark A. Matulenko, Ernest S. Paight, Robin R. Frey, Arthur Gomtsyan, Stanley DiDomenico Jr., Meiqun Jiang, Chih-Hung Lee, Andrew O. Stewart, Haixia Yu, Kathy L. Kohlhaas, Karen M. Alexander, Steve McG

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 515 KB

english, 2007

3

Subtype-selective Nav1.8 sodium channel blockers: Identification of potent, orally active nicotinamide derivatives

Michael E. Kort, Robert N. Atkinson, James B. Thomas, Irene Drizin, Matthew S. Johnson, Matthew A. Secrest, Robert J. Gregg, Marc J.C. Scanio, Lei Shi, Ahmed H. Hakeem, Mark A. Matulenko, Mark L. Chap

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 508 KB

english, 2010

4

Pyridopyrimidine analogues as novel adenosine kinase inhibitors

Guo Zhu Zheng, Chih-Hung Lee, John K Pratt, Richard J Perner, Mei Qun Jiang, Arthur Gomtsyan, Mark A Matulenko, Yui Mao, John R Koenig, Ki H Kim, Steve Muchmore, Haixia Yu, Kathy Kohlhaas, Karen M Ale

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 384 KB

english, 2001

5

Design, Synthesis, and Structure−Activity Relationship of 6-Alkynylpyrimidines as Potent Adenosine Kinase Inhibitors

Gomtsyan, Arthur, Didomenico, Stanley, Lee, Chih-Hung, Matulenko, Mark A., Kim, Ki, Kowaluk, Elizabeth A., Wismer, Carol T., Mikusa, Joe, Yu, Haixia, Kohlhaas, Kathy, Jarvis, Michael F., Bhagwat, Shri

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 149 KB

english, 2002

6

Substituted Indazoles as Na V 1.7 Blockers for the Treatment of Pain

Frost, Jennifer M, DeGoey, David A., Shi, Lei, Gum, Rebecca J, Fricano, Meagan M, Lundgaard, Greta L, El-Kouhen, Odile F, Hsieh, Gin C, Neelands, Torben R, Matulenko, Mark A, Daanen, Jerome F, Pai, Ma

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 951 KB

english, 2016

7

ChemInform Abstract: Total Synthesis of (+)-Breynolide.

Steven D. Burke, Jeffrey J. Letourneau, Mark A. Matulenko

Journal:

Year:

1999

File:

PDF, 32 KB

1999

8

Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists

Mark A Matulenko, Ahmed A Hakeem, Teodozyi Kolasa, Masaki Nakane, Marc A Terranova, Marie E Uchic, Loan N Miller, Renjie Chang, Diana L Donnelly-Roberts, Marian T Namovic, Robert B Moreland, Jorge D B

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 387 KB

english, 2004

9

5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure–activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors

Mark A. Matulenko, Chih-Hung Lee, Meiqun Jiang, Robin R. Frey, Marlon D. Cowart, Erol K. Bayburt, Stanley DiDomenico, Gregory A. Gfesser, Arthur Gomtsyan, Guo Zhu Zheng, Jeffery A. McKie, Andrew O. St

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

10

Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists

Xueqing Wang, Pramila A. Bhatia, Jerome F. Daanen, Steve P. Latsaw, Jeffrey Rohde, Teodozyi Kolasa, Ahmed A. Hakeem, Mark A. Matulenko, Masaki Nakane, Marie E. Uchic, Loan N. Miller, Renjie Chang, Rob

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 286 KB

english, 2005

11

Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand

Mark A. Matulenko, Bruce Surber, Leimin Fan, Teodozyi Kolasa, Masaki Nakane, Marc A. Terranova, Marie E. Uchic, Loan N. Miller, Renjie Chang, Diana L. Donnelly-Roberts, Marian T. Namovic, Robert B. Mo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 265 KB

english, 2004

12

Diastereoselectivity enhancement in vinylcuprate addition to β-alkoxyaldehydes via a vinylsilane.

Steven D. Burke, Anthony D. Piscopio, Brian E. Marron, Mark A. Matulenko, Gonghua Pan

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 159 KB

english, 1991

13

Total synthesis of (+)-breynolide

Steven D. Burke, Jeffery J. Letourneau, Mark A. Matulenko

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 250 KB

english, 1999

14

[3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor

Robert B. Moreland, Marc A. Terranova, Renjie Chang, Marie E. Uchic, Mark A. Matulenko, Bruce W. Surber, Andrew O. Stewart, Jorge D. Brioni

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 286 KB

english, 2004

15

1-Aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one Oximes as Potent Dopamine D4 Receptor Agonists for the Treatment of Erectile Dysfunction

Matulenko, Mark A., Hakeem, Ahmed A., Patel, Meena V., Mortell, Kathleen, Bhatia, Pramila, Henry, Rodger, Nakane, Masaki, Hsieh, Gin C., Terranova, Marc A., Kolasa, Teodozyj

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

16

A-887826 is a structurally novel, potent and voltage-dependent Nav1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats

Xu-Feng Zhang, Char-Chang Shieh, Mark L. Chapman, Mark A. Matulenko, Ahmed H. Hakeem, Robert N. Atkinson, Michael E. Kort, Brian E. Marron, Shailen Joshi, Prisca Honore, Connie R. Faltynek, Douglas S.

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

17

Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels

G.R. Dubé, Sonya G. Lehto, Nicole M. Breese, Scott J. Baker, Xueqing Wang, Mark A. Matulenko, Prisca Honoré, Andrew O. Stewart, Robert B. Moreland, Jorge D. Brioni

Journal:

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

18

Corrigendum to “Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels” [Pain 117 (2005) 88–96]

G.R. Dubé, Sonya G. Lehto, Nicole M. Breese, Scott J. Baker, Xueqing Wang, Mark A. Matulenko, Prisca Honoré, Andrew O. Stewart, Robert B. Moreland, Jorge D. Brioni

Journal:

Year:

2005

Language:

english

File:

PDF, 70 KB

english, 2005

19

Solvatochromic Solvent Polarity Measurements In Analytical Chemistry: Synthesiss And Applications Of Et-30

Johnson, Bruce P., Gabrielsen, Bjarne, Matulenko, Mark, Dorsey, John G., Reichardt, Christian

Journal:

Analytical Letters

Year:

1986

Language:

english

File:

PDF, 725 KB

english, 1986

20

Dopamine D 4 Ligands and Models of Receptor Activation: 2-(4-Pyridin-2-ylpiperazin-1-ylmethyl)-1 H -benzimidazole and Related Heteroarylmethylarylpiperazines Exhibit a Substituent Effect Responsible for Additional Efficacy Tuning

Stewart, Andrew O., Cowart, Marlon D., Moreland, Robert B., Latshaw, Steve P., Matulenko, Mark A., Bhatia, Pramila A., Wang, Xueqing, Daanen, Jerome F., Nelson, Sherry L., Terranova, Marc A., Namovic,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 181 KB

english, 2004

21

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A

DeGoey, David A., Randolph, John T., Liu, Dachun, Pratt, John, Hutchins, Charles, Donner, Pamela, Krueger, A. Chris, Matulenko, Mark, Patel, Sachin, Motter, Christopher E., Nelson, Lissa, Keddy, Ryan,

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 606 KB

english, 2014

22

Encyclopedia of Reagents for Organic Synthesis || Bis(trimethylsilyl) Sulfide

Matulenko, Mark A.

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

23

Total Synthesis of (−)-Tetrahydropalmatine via Chiral Formamidine Carbanions: Unexpected Behavior with Certain Ortho-Substituted Electrophiles

Matulenko, Mark A., Meyers, A. I.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 397 KB

english, 1996

24

Crystal Structures of Human Adenosine Kinase Inhibitor Complexes Reveal Two Distinct Binding Modes †

Muchmore, Steven W., Smith, Richard A., Stewart, Andrew O., Cowart, Marlon D., Gomtsyan, Arthur, Matulenko, Mark A., Yu, Haixia, Severin, Jean M., Bhagwat, Shripad S., Lee, Chih-Hung, Kowaluk, Elizabe

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

25

Discovery of 3-Methyl- N -(1-oxy-3‘,4‘,5‘,6‘-tetrahydro-2‘ H -[2,4‘-bipyridine]-1‘-ylmethyl)benzamide (ABT-670), an Orally Bioavailable Dopamine D 4 Agonist for the Treatment of Erectile Dysfunction

Patel, Meena V., Kolasa, Teodozyj, Mortell, Kathleen, Matulenko, Mark A., Hakeem, Ahmed A., Rohde, Jeffrey J., Nelson, Sherry L., Cowart, Marlon D., Nakane, Masaki, Miller, Loan N., Uchic, Marie E., T

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

26

Highlights of the Structure Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the HCV NS5A Inhibitor Pibrentasvir (ABT-530)

Wagner, Rolf, Randolph, John T., Patel, Sachin V., Nelson, Lissa T., Matulenko, Mark A., Keddy, Ryan, Pratt, John K., Liu, Dachun, Krueger, A. Chris, Donner, Pamela L., Hutchinson, Douglas K., Flentge

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 972 KB

english, 2018

27

Voltage-Gated Sodium Channel Blockers for the Treatment of Chronic Pain

Matulenko, Mark, Scanio, Marc, Kort, Michael

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

28

Voltage-Gated Sodium Channel Blockers for the Treatment of Chronic Pain

Matulenko, Mark, Scanio, Marc, Kort, Michael

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

File:

PDF, 377 KB

2009